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Unlock Your Cellular Potential: Measuring and Optimizing NAD+ Levels

Track your NAD+ levels and implement strategies to boost cellular energy and longevity.

You can’t hack what you don’t measure. Testing your biomarkers is how you take control of your biology.

Dave Asprey

Hello Capilli Eternal Community,

As Dave Asprey wisely said, understanding and optimizing your health starts with measuring it. NAD⁺ (nicotinamide adenine dinucleotide) is one of the most critical molecules for energy production, cellular repair, and healthy aging—yet its levels naturally decline with age.

In this edition of our Mitochondria & NAD⁺ series, we’ll explore how to measure your NAD⁺ levels, interpret the results, and implement advanced strategies to optimize them. From at-home testing kits to practical protocols, this guide will empower you to take charge of your cellular health.

Why Measure NAD⁺ Levels?

NAD⁺ (nicotinamide adenine dinucleotide) is essential for mitochondrial function, cellular repair, and overall energy production. Tracking your NAD⁺ levels can help you:

  • Understand your baseline health and cellular efficiency.

  • Monitor improvements when implementing lifestyle or supplement protocols.

  • Identify potential deficiencies that may hinder energy and vitality.

How to Test NAD⁺ Levels

At-Home Testing Kits

Modern technology has made NAD⁺ testing more accessible, allowing you to track your levels from the comfort of your home.

How It Works:

  • Collect a simple blood or saliva sample using a kit provided by the testing company.

  • Ship the sample to a lab for analysis.

Pros: Convenient and easy to use.

Cons: Results may vary depending on the quality of the kit.

Examples of At-Home Tests:

Clinical Testing Options

For more comprehensive and accurate results, clinical testing is the gold standard. This often includes:

  • Blood Plasma NAD⁺ Levels: Measured to assess cellular energy balance.

  • Metabolite Analysis: Provides a detailed overview of NAD⁺ precursors and related metabolites.

Consult a healthcare provider for access to these tests.

Advanced Protocols for Optimizing NAD⁺ Levels

Once you know your NAD⁺ baseline, here’s how to optimize it:

Lifestyle Strategies

  • Exercise Regularly: Aerobic and resistance training stimulate NAD⁺ production.

  • Intermittent Fasting: Promotes autophagy and supports NAD⁺ levels.

  • Sleep Optimization: Restful sleep helps maintain optimal cellular repair.

Dietary Recommendations

Incorporate NAD⁺-boosting foods into your diet:

  • Turkey, Salmon, and Chicken: Rich in vitamin B3, a precursor to NAD⁺.

  • Leafy Greens and Mushrooms: Support antioxidant defenses and mitochondrial health.

Supplementation

Consider adding these NAD⁺ precursors:

  • NMN (Nicotinamide Mononucleotide): Start with 250–500 mg daily.

  • NR (Nicotinamide Riboside): Typical dose: 300–500 mg daily.

Synergistic Options:

  • Resveratrol and Quercetin: Activate sirtuins and complement NAD⁺ precursors.

  • CoQ10 and PQQ: Enhance mitochondrial energy production.

Cycling Protocols:

Use supplements for 8–12 weeks, followed by a break to allow the body to reset.

Case Study: A Path to Cellular Health

Meet Sarah, a 42-year-old professional experiencing fatigue and brain fog. After testing her NAD⁺ levels, she discovered a significant deficiency. By incorporating a protocol of intermittent fasting, NMN supplementation, and regular exercise, she experienced:

  • Increased energy levels within 3 weeks.

  • Improved focus and mental clarity after 2 months.

  • Noticeable gains in physical endurance by the 3-month mark.

Tracking her progress through at-home NAD⁺ tests showed a steady rise in her levels, aligning with her improved well-being.

Expand Your Knowledge

Recommended Resources:

  1. NAD⁺ Metabolism and Aging

    • Summary: This article explores how NAD⁺ influences key cellular functions, including metabolic pathways, DNA repair, and chromatin remodeling, and its role in the aging process.

    • Link: NAD⁺ Metabolism and Aging

  2. NAD⁺ Supplementation: Navigating Dosage and Safety

YouTube Video:

For a comprehensive understanding of how to boost NAD⁺ levels through supplements and diet, you might find this video helpful:

This video discusses the pros and cons of various NAD⁺ supplements and explores natural ways to enhance NAD⁺ levels through diet and lifestyle modifications.

What’s Next?

In our next installment of the Mitochondria & NAD⁺ series, we’ll explore innovative therapies and emerging research that can further enhance mitochondrial health and longevity.

Stay tuned for actionable insights and the latest advancements in optimizing cellular energy. Don’t forget to subscribe to our newsletter and join us on this journey to better health and vitality!

To your health and vitality,
The Capilli Eternal Team

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