🔬TODAY’S BREAKTHROUGH
Longevity medicine is shifting from reactive treatment to proactive prevention. A new comprehensive review introduces the Longevity Pyramid, a structured framework designed to help you understand and apply the various strategies for extending healthy lifespan.
The Discovery:
Researchers have created an innovative conceptual framework that outlines progressive levels of interventions, providing a roadmap for modern preventative healthcare. Starting with foundational strategies like advanced diagnostics and lifestyle changes, the pyramid progresses to more personalized and advanced interventions, guiding individuals toward a more nuanced and strategic approach to healthy aging.
The Science:
The foundation of the Longevity Pyramid is Diagnostics and Analysis, using advanced tools like genetic testing and biological age biomarkers for early detection.
The next level focuses on Lifestyle Interventions through diet, exercise, and social and mental well-being.
The third level addresses Dietary Supplements, including NAD+ precursors and senolytics.
The fourth level is Pharmacological and Non-pharmacological Interventions, such as metformin, rapamycin, and hyperbaric oxygen therapy.
The final level is Experimental Strategies, which includes gene editing and stem cell therapies for future applications.
Your Action:
Start with the base of the pyramid. Focus on foundational pillars like exercise and a healthy diet, which have the most robust evidence for improving healthspan. Consider advanced diagnostics as a tool for personalizing your strategy, guiding you on where to focus your efforts for maximum impact on your long-term health.
Bottom Line:
Extending your lifespan and healthspan requires a structured, evidence-based approach, starting with prevention and lifestyle.
Source:
Climbing the longevity pyramid: overview of evidence-driven healthcare prevention strategies for human longevity, Frontiers in Aging, Anđela Martinović, et al., November 26, 2024 https://www.frontiersin.org/journals/aging/articles/10.3389/fragi.2024.1495029/full
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Disclaimer:
This newsletter is for informational purposes only and does not substitute professional medical advice. Always consult with a healthcare provider before making any changes to your health regimen.