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Fasting and the Brain
How fasting supports mental clarity, protects neurons, and fuels long-term brain health
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Fasting is not a punishment. It is a biological reset button.
Hello Capilli Eternal Community,
The brain is one of the most energy-hungry organs in your body.
But it also thrives under the right kind of stress.
Fasting is one of those stressors. Research shows it may enhance focus, protect against cognitive decline, and even stimulate the growth of new neurons.
Let’s explore how giving your body less can help your mind become more.
Mental Clarity Starts with Metabolic Shift
When you fast, your body runs low on glucose and begins producing ketones. These are clean-burning fuel molecules made from fat.
Unlike blood sugar, ketones:
Reduce oxidative stress in neurons
Provide more efficient energy to the brain
Activate protective genes linked to learning and memory
Many people report sharper mental clarity, elevated mood, and better concentration while fasting. Scientific evidence supports these experiences.
BDNF: The Brain’s Fertilizer
Fasting has been shown to increase BDNF (Brain-Derived Neurotrophic Factor), a protein that:
Stimulates the formation of new synapses
Supports the growth of new brain cells
Protects against neurodegeneration
Low BDNF levels are linked to depression, anxiety, Alzheimer’s, and Parkinson’s.
Fasting, along with exercise and deep sleep, is one of the most effective ways to raise it.
Neuroprotection and Longevity
Studies in both animals and humans suggest that fasting may:
Delay cognitive aging
Protect brain cells from injury or toxic buildup
Reduce the risk of Alzheimer’s and Parkinson’s
Improve adaptability through metabolic switching
This process is called hormesis. It is a mild biological stress that makes the system stronger over time.
Your brain becomes more resilient by learning to thrive without constant energy intake.
Fasting and Neurogenesis
Fasting stimulates neurogenesis. This is the formation of new neurons in the hippocampus, a brain region critical for memory and emotional regulation.
It also increases autophagy in the brain. This helps clear out damaged proteins and waste materials that accumulate with age.
Together, these effects may explain why fasting supports greater mood balance and cognitive sharpness throughout life.
Timing and Duration
12 to 16 hours: Ketone production begins and mental clarity improves
24 hours: BDNF increases and stress-resistance genes activate
48 hours or more: Neuronal autophagy rises and brain renewal deepens
Even time-restricted eating (16:8) practiced regularly can support long-term cognitive health.
🔍 Expand Your Knowledge
📖 Scientific Article
🎥 Watch This
Dr. Mark Mattson on Fasting and Brain Health
🔗 Watch on YouTube (TEDx talk from the neuroscientist who pioneered brain fasting research)
What’s Next?
In our next edition, we’ll explore how fasting improves metabolic health and insulin sensitivity. This affects not only energy and weight, but also inflammation and chronic disease risk.
To your health and vitality,
The Capilli Eternal Team
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Disclaimer:
This newsletter is for informational purposes only and does not substitute professional medical advice. Always consult with a healthcare provider before making any changes to your health regimen.